KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
19.39
Human Site:
S249
Identified Species:
35.56
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
S249
A
V
I
P
I
N
G
S
P
R
T
P
R
R
G
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
S396
A
V
I
P
I
N
G
S
P
R
T
P
R
R
G
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
S249
A
V
I
P
I
N
G
S
P
R
T
P
R
R
G
Dog
Lupus familis
XP_534118
897
103170
R224
G
S
P
R
T
P
R
R
G
Q
N
R
S
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
S243
A
A
I
P
I
N
G
S
P
R
T
P
R
R
G
Rat
Rattus norvegicus
P33568
920
105007
S242
A
A
T
P
I
N
G
S
P
R
T
P
R
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
N234
A
V
T
A
I
P
I
N
G
S
P
R
T
S
R
Chicken
Gallus gallus
Q90600
921
104417
N237
A
V
T
A
L
T
V
N
G
S
T
R
T
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
S235
V
V
S
S
S
T
L
S
P
P
T
R
T
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
N233
P
S
N
F
N
D
E
N
Y
T
P
P
Q
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
S114
S
F
S
D
T
V
K
S
S
L
M
A
L
K
Q
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
L276
G
D
K
G
V
D
L
L
A
S
L
C
N
K
Y
Maize
Zea mays
Q3LXA7
1010
111475
I259
S
D
R
G
V
S
L
I
A
S
L
C
E
K
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
0
N.A.
93.3
86.6
N.A.
20
20
N.A.
26.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
86.6
N.A.
26.6
33.3
N.A.
26.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
16
0
16
0
0
0
0
16
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
16
0
8
0
16
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
16
0
0
39
0
24
0
0
0
0
0
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
31
0
47
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
0
0
0
24
0
% K
% Leu:
0
0
0
0
8
0
24
8
0
8
16
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
8
39
0
24
0
0
8
0
8
0
0
% N
% Pro:
8
0
8
39
0
16
0
0
47
8
16
47
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% Q
% Arg:
0
0
8
8
0
0
8
8
0
39
0
31
39
39
31
% R
% Ser:
16
16
16
8
8
8
0
54
8
31
0
0
8
16
0
% S
% Thr:
0
0
24
0
16
16
0
0
0
8
54
0
24
8
0
% T
% Val:
8
47
0
0
16
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _